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Isobel Gamble is the protagonist and narrator of Hester. A Scottish seamstress married to Edward, an apothecary who struggles with addiction and debts, Isobel arrives in America hopeful for a future of her own making. She is talented and hardworking, though taught to fear her “colors,” her name for synesthesia. Over the course of the novel, she learns to respect her colors as well as her ancestress and namesake Isobel Gowdie, a woman who was accused of being a witch. Through bonds made in Salem, Isobel learns to move on from the past and prepare for a future with Margaret, her daughter by Nat Hathorne (who later goes by Nathaniel Hawthorne). She is prone to romance, becoming infatuated with Nat despite his objectification of her, and eventually falling in love with her friend Captain Willian Darling, who treats her with respect. She also begins the novel ignorant about matters of race and slavery, particularly in an American context, and learns to empathize with her friend Mercy’s family as they navigate a racist society.
Nat Hathorne is a fictionalized version of American author Nathaniel Hawthorne, and much of his characterization is based on Hawthorne’s biographical details. Nat is a love interest to Isobel, though he abandons her when she becomes pregnant with his daughter, Margaret. He is brooding and self-absorbed, spending much of his time fixating on his ancestor, John Hathorne, a judge in the Salem Witch Trials. He imagines Isobel as one of his literary creations, which makes it impossible for him to understand her as a person. However, Nat is hypocritical, as he accuses a pregnant Isobel of bewitching him, of being in control, to alleviate himself of guilt or responsibility. He is dismissive of injustices that do not concern him, such as slavery, and by the end of the novel, Isobel recognizes this and declines his offer to move to Maine. He goes on to write The Scarlet Letter, with protagonist Hester Prynne being based on her. Like Edward, Nat’s toxic masculinity manifests as irresponsibility.
Edward Gamble is Isobel’s husband and antagonist. While he begins the novel as an accomplished apothecary, he becomes a barrier to her economic stability: In Scotland, he accumulates debts to the point of him and Isobel being sentenced to live in a poorhouse, while in Salem, he steals her money to finance his scheme to discover the “elixir of life” by studying African and Native medicine. Edward disappears for much of the novel due to Darling having him arrested in Jamaica after he threatened Darling’s plan to help people who escaped slavery. He returns to Salem to return Mercy’s family to their enslaver to receive reward money. Like Nat, Edward’s toxic masculinity manifests as irresponsibility—and later, violence against Isobel.
Mercy is Isobel’s neighbor and friend, a Black woman and fellow seamstress. She lives in Salem with her adopted children, Ivy and Abraham, and cousin Zeke. Initially hesitant to deepen her relationship with Isobel, she eventually warms up to her and offers advice on how to survive as a marginalized person in America—though her position as a Black woman is more precarious than Isobel’s as a Scottish woman. Isobel learns to stitch messages into embroidery from Mercy’s work, which strikes Isobel as “magic.” Mercy is more pragmatic about her talent, framing it not as witchcraft but a tool that women and Black people can use to gain power in a world set against them. At the end of the novel, she is revealed to be aiding escapees from slavery and when Isobel flees to Canada, Mercy stays behind to continue her work in abolitionism.
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